Optimal design of protein-coding sequences

COSMO (Codon Optimization Strategy with Multiple Objectives) is a multicriterion codon optimization algorithm based on dynamic programming. For non-academic or commercial use, please contact the author (A.T.).

The follwing gipped files include source codes, utility Python scripts, sample inputs, and README.txt in which example COSMO commands are written.

We have tested these files with CentOS 6 (x86_64), Ubuntu 16 (x86_64).

The following gipped file includes coding sequences used in the benchmarking.

Akito Taneda and Kiyoshi Asai, COSMO: A dynamic programming algorithm for multicritera codon optimization, submitted.